Structure of Artemia franciscana sarco/endoplasmic reticulum Ca-ATPase gene.

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چکیده

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Artemia franciscana

Artemia franciscana C. Drewes (updated, 2002) http://www.zool.iastate.edu/~c_drewes/ http://www.zool.iastate.edu/~c_drewes/Artemph.jpg Taxonomy Phylum: Arthropoda Subphylum): Crustacea Class: Branchiopoda (includes fairy shrimp, brine shrimp, daphnia, clam shrimp, tadpole shrimp) Order: Anostraca (brine shrimp and fairy shrimp) Genus and species: Artemia franciscana (= the North American versio...

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Sarcoendoplasmic reticulum Ca(2+) ATPase. A critical target in chlorine inhalation-induced cardiotoxicity.

Autopsy specimens from human victims or experimental animals that die due to acute chlorine gas exposure present features of cardiovascular pathology. We demonstrate acute chlorine inhalation-induced reduction in heart rate and oxygen saturation in rats. Chlorine inhalation elevated chlorine reactants, such as chlorotyrosine and chloramine, in blood plasma. Using heart tissue and primary cardio...

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Alternative Biotest on Artemia franciscana

Recent toxicology, in accordance with recommendations from the European Council, has demanded decrease in the number of vertebrates used in toxicology testing and their partial replacement with invertebrate animals, plants or even organ, tissue, or cell cultures. During the last 50 years various invertebrate species have been tested for their sensitivity to many chemical or physical agents to p...

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Ca-ATPase in Cardiac Sarcoplasmic Reticulum

We have studied the effects of the local anesthetic lidocaine, and the general anesthetic halothane, on the function and oligomeric state of the Ca-ATPase in cardiac sarcoplasmic reticulum (SR). Oligomeric changes were detected by timeresolved phosphorescence anisotropy (TPA). Lidocaine inhibited and aggregated the Ca-ATPase in cardiac SR. Micromolar calcium or 0.5 M lithium chloride protected ...

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Overexpression of Sarcoendoplasmic Reticulum Calcium ATPase 2a Promotes Cardiac Sympathetic Neurotransmission via Abnormal Endoplasmic Reticulum and Mitochondria Ca2+ Regulation

Reduced cardiomyocyte excitation-contraction coupling and downregulation of the SERCA2a (sarcoendoplasmic reticulum calcium ATPase 2a) is associated with heart failure. This has led to viral transgene upregulation of SERCA2a in cardiomyocytes as a treatment. We hypothesized that SERCA2a gene therapy expressed under a similar promiscuous cytomegalovirus promoter could also affect the cardiac sym...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1994

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)99976-x